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Wellness and Longevity

NAD+ Shots in Portland, OR

A quick NAD+ injection given after a health review by our medical team, on its own or as a booster added to your IV therapy appointment.

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The Basics

What a NAD+ Shot Is

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell. Cells rely on it to turn food into usable energy, to repair DNA and to support healthy brain function. Levels fall naturally as we age, which is why many patients add NAD+ to a longevity-focused routine.

A NAD+ shot delivers it by injection into the upper arm in a short visit. It is the quick alternative to a full infusion: you can book it as a stand-alone appointment, or add it as a booster when you come in for IV therapy.

WhereUpper arm, with a small needle
Injection timeOnly moments
DowntimeNone; back to your day
A glass vial of injectable NAD+ with a silver cap on a white surface
Choosing a Format

Shot, IV or Capsule: How They Compare

We offer two ways to receive NAD+: a shot and NAD+ IV therapy. Many patients also ask how both compare with the capsules sold online, so here is the plain version.

 NAD+ ShotNAD+ IV TherapyOral Capsule
How it is givenInjection into the upper armInfusion into a vein over a longer sessionSwallowed daily at home
Time in our officeA short visit; the injection takes momentsA longer infusion appointmentNone
What it containsNAD+ itselfNAD+ itself, delivered into the bloodstreamUsually precursors the body must convert after digestion
Medical oversightHealth review by our team firstHealth review by our team firstSelf-directed
Pairs well withAn IV therapy visit, as a boosterPatients who prefer an infusionAsk us before combining with a shot

Not sure which suits you? We help you choose at your health review, including whether a shot paired with IV therapy fits your goals.

Candidates

Who Chooses a NAD+ Shot

NAD+ shots may suit healthy adults who want convenient wellness support. These are the patients we see most often.

01

Longevity-Minded Adults

Healthy adults focused on aging well who want to replenish a coenzyme that declines with age.

02

People Who Feel Run Down

Patients interested in supporting cellular energy alongside sleep, nutrition and exercise.

03

Short on Time

Patients who cannot fit a full infusion into their week and prefer a visit measured in minutes.

04

IV Therapy Patients

People already on our IV therapy menu who want to add NAD+ as a booster at the same visit.

If you are pregnant or breastfeeding, or you manage a medical condition, we may ask you to check with your physician first.

What to Expect

Your Visit, Step by Step

  1. Health Review

    We go over your medical history, medications, supplements, allergies and wellness goals to confirm a NAD+ shot is appropriate.

  2. Preparation

    The injection site on your upper arm is cleaned, and we answer any last questions.

  3. Injection

    The NAD+ shot is given with a small needle. The injection itself takes only moments.

  4. Back to Your Day

    There is no downtime. Mild soreness, redness or a small bruise at the site can last a day or so.

Before Your Shot

No special preparation is needed. Eat normally, stay hydrated and wear a top that leaves your upper arm easy to reach.

After Your Shot

Keep drinking water and avoid rubbing the injection site. Tell our team about any reaction that feels unusual.

Straight Answers

What NAD+ Shots Can and Cannot Do

NAD+ injections get a lot of attention, and research on them is still developing. We would rather you book with clear expectations, so this is where we stand.

A NAD+ Shot Can

  • Replenish a coenzyme your cells use to produce energy
  • Fit a longevity routine in a visit of a few minutes
  • Add to an IV therapy appointment as a booster
  • Be paired with our team's review of your health and goals

A NAD+ Shot Cannot

  • Replace medical care for a diagnosed condition
  • Stand in for sleep, nutrition and exercise
  • Melt belly fat or act as a weight-loss treatment
  • Promise the same result for everyone; individual results vary
Dr. Natalie Mesnier, MD, smiling in green medical scrubs against a soft gray backdrop
Our Practice

Founded by Dr. Natalie Mesnier, MD

MD, Founder

Dr. Mesnier founded Ortho-Rejuv Wellness and Aesthetics. She holds certifications in advanced aesthetic procedures, including PRP and neuromodulator applications.

NAD+ shots and our other wellness services are provided by our team of Certified Advanced Estheticians and medical staff. Every NAD+ shot starts with a health review, and our team helps you choose a shot, an infusion or a combination with IV therapy that matches your goals.

Pricing

NAD+ Shot Pricing and Financing

NAD+ shots are offered as single visits or as a booster add-on to IV therapy, and members of our wellness program receive member pricing. Current rates are listed on our medspa pricing page.

Monthly payment plans are available through our financing partner, Cherry.

FAQ

NAD+ Shot Questions, Answered

Have a question that is not here? Bring it to your free consultation and our team will walk through it with you.

How is a NAD+ shot different from NAD+ pills?

Most capsules sold as NAD+ support contain precursors that your body has to convert after digestion. A shot places NAD+ itself into the tissue, so it does not depend on the gut. Capsules are taken daily at home, while a shot is a short in-office visit given after a health review.

Does NAD+ reduce belly fat?

We do not offer NAD+ shots as a weight-loss or fat-reduction treatment. NAD+ plays a role in how cells produce energy, but it is not a substitute for nutrition, exercise or a medical weight plan. If body contouring is your goal, ask us about T-Shape 2 at your consultation.

What should I avoid after a NAD+ injection?

There is no downtime, so you can go back to your day right away. Avoid rubbing or pressing on the injection site, keep drinking water, and expect that the spot may feel sore or look a little red for a day or so. Let our team know about any reaction that feels unusual.

How can I tell if NAD+ is working?

There is no single sign, and individual results vary. Many patients keep simple notes on energy, focus and sleep over several weeks of shots, then review them with our team to decide whether to continue.

Can I add a NAD+ shot to my IV therapy appointment?

Yes. A NAD+ shot can be a stand-alone visit or a booster added to an IV therapy appointment. Patients who prefer a longer infusion can choose NAD+ IV therapy instead.

How long does a NAD+ shot visit take?

The injection itself takes only moments, so a NAD+ shot fits into a short visit. Your first visit also includes a health review with our team before the shot is given.

Can I get a NAD+ shot if I am pregnant or have a medical condition?

If you are pregnant or breastfeeding, or you manage a medical condition, we may ask you to check with your physician first. Our team reviews your history, medications, supplements and allergies before any shot is given.

Portland, OR

Book Your NAD+ Shot in Portland

Start with a free consultation or book your shot directly. We can add it to your next IV therapy visit.

Visit us: 5050 NE Hoyt St #626, Portland, OR 97213 Providence Plaza, across the street from Providence Hospital Open Monday to Saturday
Venus Nova, Certified Advanced Esthetician at Ortho-Rejuv

Venus is a Certified Advanced Esthetician, Certified Phlebotomy Technician, and pre-nursing student with a passion for medical aesthetics and patient-centered care. She is dedicated to helping clients achieve healthy, radiant skin through result-driven, customized treatments tailored to their unique needs. As a patient advocate at heart, Venus loves working with all skin types and creating long-term skincare plans that focus on both visible results and overall skin health.

Her favorite treatments include Aerolase, NeoGen, and microneedling, innovative treatment options that deliver real, transformative outcomes. Outside of the treatment room, Venus enjoys creating social media content, exploring new food spots, and spending time with friends and family

Woman with long brown hair wearing black healthcare uniform against gray background

Certified Advanced Esthetician

Woman with long dark hair smiling at camera against white background
Katherine is a Certified Advanced Esthetician dedicated to helping every client feel confident and comfortable in their skin. She takes a personalized approach to skincare, creating customized treatment plans and at-home routines that work for you. Katherine is passionate about finding effective, thoughtful skincare solutions for all skin types and tones, with a special emphasis on acne-prone skin. She aims to provide a safe space in the treatment room to ensure every client feels welcomed and supported no matter where they are in their journey. She looks forward to meeting you soon!
Nancy, woman with long brown wavy hair wearing black top, smiling at camera
Dr. Nancy Yen Shipley experienced in the use of ultrasound and orthobiologics in the treatment of musculoskeletal conditions. And is additionally certified in Laser treatment of medical conditions, post-surgical and post-traumatic scars, PRP, injectable neuromodulators for medical and aesthetic applications.
Kyline, woman wearing white coat and gold chain necklace, smiling at camera
Ms. Kylie Farwell is a board-certified Physician Assistant and a native Idahoan. Trained in orthobiologics, PRP, ultrasound-guided interventions, laser therapy, and neuromodulators such as botox, and fillers, Kylie is passionate about helping patients overcome their post-surgical and post-traumatic scars, and present their best selves forward to the world.
Natalie, woman with shoulder-length dark hair wearing black top and pearl necklace

Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv Wellness and Aesthetics, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.