A quick antioxidant injection given after a health review by our medical team, booked on its own or added as a booster to your IV therapy visit.
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Glutathione is an antioxidant your body makes from three amino acids. It helps neutralize free radicals and supports natural detoxification, much of it in the liver.
A glutathione shot delivers it by injection, so it skips the digestive tract that breaks down much of what you swallow. That is why many patients choose a shot over a capsule. It is also a common part of a skin health routine for patients who want a brighter-looking complexion.
We give glutathione two ways in our office. Patients often ask how both compare with the capsules sold online.
Not sure which fits? We help you choose at your health review, including whether a shot paired with IV therapy suits your goals.

Glutathione shots may suit healthy adults who want convenient wellness support. These are the patients we see most often.
Many glutathione searches are about lightening skin. We would rather you book with clear expectations, so this is where we stand.
If dark spots or uneven tone are your main concern, our laser treatments for hyperpigmentation issues such as melasma treat pigment directly. We can map out both at a free consultation.
We go over your medical history, current medications and supplements, allergies and wellness goals to confirm a glutathione shot is right for you.
The injection site on your upper arm is cleaned, and we answer any last questions.
The shot is given with a small needle. If you are here for IV therapy, it can be added during the same visit.
There is no downtime. Mild soreness, redness or a small bruise at the site can last a day or so; tell us about any reaction that feels unusual.
No special preparation is needed. Eat normally, stay hydrated and wear a top that leaves your upper arm easy to reach.
MD, Founder
Dr. Mesnier founded our Portland medical spa. She holds certifications in advanced aesthetic procedures, including PRP and neuromodulator applications.
Our team of certified advanced estheticians and medical staff provides our wellness services. Every glutathione shot starts with a health review, and our team helps you choose a shot, an infusion or a combination with IV therapy.

Glutathione shots are offered as single visits or as a booster add-on to IV therapy, and members of our wellness program receive member pricing. Current rates are listed on our medspa pricing page.
Monthly payment plans are available through our financing partner, Cherry.
Have a question that is not here? Bring it to your free consultation and our team will walk through it with you.
Yes. Many patients add a glutathione shot as a booster during an IV therapy visit, so both are done in one trip. Tell us when you book and we will plan the two together.
There is no single schedule that suits everyone. We set a plan at your health review based on your goals, your other wellness treatments and how you respond, and we adjust it over time.
We offer glutathione shots for antioxidant and skin health support, not to change your natural skin tone. If dark spots, melasma or uneven tone are your main concern, our laser and skin treatments target pigment directly, and we can talk through those at a free consultation.
The shot uses a small needle and the injection itself takes only moments. Some patients notice mild soreness, redness or a small bruise at the site for a day or so, and most go straight back to work.
Tell us at your health review. If you are pregnant or breastfeeding, or you manage a medical condition, we may ask you to check with your physician before your first shot.
Start with a free consultation, or book your shot directly. We can add it to your next IV therapy visit.

Venus is a Certified Advanced Esthetician, Certified Phlebotomy Technician, and pre-nursing student with a passion for medical aesthetics and patient-centered care. She is dedicated to helping clients achieve healthy, radiant skin through result-driven, customized treatments tailored to their unique needs. As a patient advocate at heart, Venus loves working with all skin types and creating long-term skincare plans that focus on both visible results and overall skin health.
Her favorite treatments include Aerolase, NeoGen, and microneedling, innovative treatment options that deliver real, transformative outcomes. Outside of the treatment room, Venus enjoys creating social media content, exploring new food spots, and spending time with friends and family

Certified Advanced Esthetician




Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv Wellness and Aesthetics, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.