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Wellness and Longevity

Glutathione Shots in Portland, OR

A quick antioxidant injection given after a health review by our medical team, booked on its own or added as a booster to your IV therapy visit.

Inside every molecule
GluGlutamate
CysCysteine
GlyGlycine
GlutathioneThree amino acids your body links into one antioxidant
  • Shot
  • IV booster add-on
  • Glutathione IV
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The Basics

What a Glutathione Shot Is

Glutathione is an antioxidant your body makes from three amino acids. It helps neutralize free radicals and supports natural detoxification, much of it in the liver.

A glutathione shot delivers it by injection, so it skips the digestive tract that breaks down much of what you swallow. That is why many patients choose a shot over a capsule. It is also a common part of a skin health routine for patients who want a brighter-looking complexion.

WhereUpper arm
Injection timeA few moments
DowntimeNone
Before your first shotA health review
Choosing a Format

Shot, IV or Capsule: Three Ways to Take It

We give glutathione two ways in our office. Patients often ask how both compare with the capsules sold online.

Our glutathione shot

A quick injection

How it is given
A small needle in the upper arm
Time in our office
A short visit; the injection takes moments
Suits
Busy schedules, or a booster added to an IV visit
Our glutathione IV

An infusion

How it is given
Delivered directly into the bloodstream through an IV
Time in our office
A longer, seated infusion appointment
Suits
Patients who prefer an infusion over a shot
Oral capsule

Taken at home

How it is given
Swallowed, then passed through digestion first
Time in our office
None
Suits
Self-directed use; ask us before combining it with shots

Not sure which fits? We help you choose at your health review, including whether a shot paired with IV therapy suits your goals.

Smiling woman with glowing skin and sleek dark hair looking back over her bare shoulder
Candidates

Who Chooses a Glutathione Shot

Glutathione shots may suit healthy adults who want convenient wellness support. These are the patients we see most often.

  • Wellness-focused adultsPeople adding antioxidant support to a routine of sleep, nutrition and exercise.
  • Patients focused on skin radianceThose building a skin health routine for every skin type and tone.
  • IV therapy patientsPeople already on our IV menu who want a booster in the same visit.
  • Short on timeAnyone who wants a visit measured in minutes, not hours.
Straight Answers

Radiance Support, Not Skin Bleaching

Many glutathione searches are about lightening skin. We would rather you book with clear expectations, so this is where we stand.

A glutathione shot can

  • Add antioxidant support that helps the body neutralize free radicals
  • Support your body's own detoxification, including liver function
  • Fit into a skin health routine aimed at a radiant-looking complexion
  • Pair with an IV therapy visit as a quick booster

A glutathione shot will not

  • Change your natural skin tone; we do not offer it for skin lightening
  • Erase melasma, sun spots or other pigment on its own
  • Replace medical care for a diagnosed condition
  • Stand in for sleep, nutrition and exercise; individual results vary

If dark spots or uneven tone are your main concern, our laser treatments for hyperpigmentation issues such as melasma treat pigment directly. We can map out both at a free consultation.

What to Expect

Your Visit, From Review to Done

  1. 01First

    Health review

    We go over your medical history, current medications and supplements, allergies and wellness goals to confirm a glutathione shot is right for you.

  2. 02Next

    Preparation

    The injection site on your upper arm is cleaned, and we answer any last questions.

  3. 03A few moments

    Injection

    The shot is given with a small needle. If you are here for IV therapy, it can be added during the same visit.

  4. 04Right after

    Back to your day

    There is no downtime. Mild soreness, redness or a small bruise at the site can last a day or so; tell us about any reaction that feels unusual.

Before your shot

No special preparation is needed. Eat normally, stay hydrated and wear a top that leaves your upper arm easy to reach.

When you can come in

  • Monday to Thursday8am to 5pm
  • Friday10am to 4pm
  • Saturday9am to 2pm
  • SundayClosed
Our Practice

Founded by Dr. Natalie Mesnier, MD

MD, Founder

Dr. Mesnier founded our Portland medical spa. She holds certifications in advanced aesthetic procedures, including PRP and neuromodulator applications.

Our team of certified advanced estheticians and medical staff provides our wellness services. Every glutathione shot starts with a health review, and our team helps you choose a shot, an infusion or a combination with IV therapy.

Dr. Natalie Mesnier, MD, founder of Ortho-Rejuv Wellness and Aesthetics
Pricing

Glutathione Shot Pricing and Financing

Glutathione shots are offered as single visits or as a booster add-on to IV therapy, and members of our wellness program receive member pricing. Current rates are listed on our medspa pricing page.

Monthly payment plans are available through our financing partner, Cherry.

FAQ

Glutathione Shot Questions

Have a question that is not here? Bring it to your free consultation and our team will walk through it with you.

Can I add a glutathione shot to my IV therapy appointment?

Yes. Many patients add a glutathione shot as a booster during an IV therapy visit, so both are done in one trip. Tell us when you book and we will plan the two together.

How often should I get a glutathione shot?

There is no single schedule that suits everyone. We set a plan at your health review based on your goals, your other wellness treatments and how you respond, and we adjust it over time.

Will a glutathione shot lighten my skin?

We offer glutathione shots for antioxidant and skin health support, not to change your natural skin tone. If dark spots, melasma or uneven tone are your main concern, our laser and skin treatments target pigment directly, and we can talk through those at a free consultation.

Does a glutathione shot hurt or need downtime?

The shot uses a small needle and the injection itself takes only moments. Some patients notice mild soreness, redness or a small bruise at the site for a day or so, and most go straight back to work.

Can I get a glutathione shot if I am pregnant or have a medical condition?

Tell us at your health review. If you are pregnant or breastfeeding, or you manage a medical condition, we may ask you to check with your physician before your first shot.

Portland, OR

Book Your Glutathione Shot in Portland

Start with a free consultation, or book your shot directly. We can add it to your next IV therapy visit.

Visit us: 5050 NE Hoyt St #626, Portland, OR 97213 Providence Plaza, across the street from Providence Hospital Open Monday to Saturday
Venus Nova, Certified Advanced Esthetician at Ortho-Rejuv

Venus is a Certified Advanced Esthetician, Certified Phlebotomy Technician, and pre-nursing student with a passion for medical aesthetics and patient-centered care. She is dedicated to helping clients achieve healthy, radiant skin through result-driven, customized treatments tailored to their unique needs. As a patient advocate at heart, Venus loves working with all skin types and creating long-term skincare plans that focus on both visible results and overall skin health.

Her favorite treatments include Aerolase, NeoGen, and microneedling, innovative treatment options that deliver real, transformative outcomes. Outside of the treatment room, Venus enjoys creating social media content, exploring new food spots, and spending time with friends and family

Woman with long brown hair wearing black healthcare uniform against gray background

Certified Advanced Esthetician

Woman with long dark hair smiling at camera against white background
Katherine is a Certified Advanced Esthetician dedicated to helping every client feel confident and comfortable in their skin. She takes a personalized approach to skincare, creating customized treatment plans and at-home routines that work for you. Katherine is passionate about finding effective, thoughtful skincare solutions for all skin types and tones, with a special emphasis on acne-prone skin. She aims to provide a safe space in the treatment room to ensure every client feels welcomed and supported no matter where they are in their journey. She looks forward to meeting you soon!
Nancy, woman with long brown wavy hair wearing black top, smiling at camera
Dr. Nancy Yen Shipley experienced in the use of ultrasound and orthobiologics in the treatment of musculoskeletal conditions. And is additionally certified in Laser treatment of medical conditions, post-surgical and post-traumatic scars, PRP, injectable neuromodulators for medical and aesthetic applications.
Kyline, woman wearing white coat and gold chain necklace, smiling at camera
Ms. Kylie Farwell is a board-certified Physician Assistant and a native Idahoan. Trained in orthobiologics, PRP, ultrasound-guided interventions, laser therapy, and neuromodulators such as botox, and fillers, Kylie is passionate about helping patients overcome their post-surgical and post-traumatic scars, and present their best selves forward to the world.
Natalie, woman with shoulder-length dark hair wearing black top and pearl necklace

Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv Wellness and Aesthetics, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.