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Wellness and Longevity

B12 Shots in Portland, OR

A quick vitamin B12 injection from our medical team, booked on its own or added as a booster to your IV therapy visit, with a health review before your first shot.

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How It Works

What a Vitamin B12 Shot Does

Vitamin B12 is an essential vitamin your body cannot make on its own, so it has to come from food or a supplement. A B12 shot places the vitamin into the muscle of the upper arm, which means it does not depend on your digestive tract to absorb it.

It is one of the quickest wellness boosters on our menu: a few moments in the chair and you are back to your day.

01

Energy Metabolism

B12 is part of the process that turns the food you eat into usable energy.

02

Red Blood Cells

Your body needs B12 to form healthy red blood cells that carry oxygen.

03

Nerve Function

B12 helps maintain the nervous system and the protective layer around nerves.

Candidates

Who Chooses a B12 Shot

B12 shots may suit healthy adults who want convenient wellness support. Our team confirms it is right for you first.

Plant-Based Eaters

B12 comes mainly from animal foods, so vegans and vegetarians often look for another source.

Low Energy

People who feel run down and want to support the way their body produces energy.

Absorption Concerns

Those who absorb B12 poorly from food, since an injection skips the gut entirely.

Busy Schedules

Patients short on time who want a wellness visit that fits between meetings.

If you are pregnant or breastfeeding, or you manage a medical condition, we may ask you to check with your physician before your first shot.

Compare Your Options

Shot, Supplement or IV Drip

B12 reaches your body three common ways. Here is how a shot at our office compares with a daily pill and with our IV therapy.

B12 ShotOral SupplementIV Therapy
How it is givenOne small injection in the upper armA pill or liquid taken by mouthA drip of fluids, vitamins and minerals into a vein
AbsorptionSkips the digestive tractDepends on how well your gut absorbs itGoes straight into the bloodstream
Time it takesThe injection takes momentsDaily, at homeA longer, seated visit
Best fitA quick, focused B12 boostRoutine maintenance when absorption is normalHydration, energy, immunity or skin goals, with B12 added if you like
What to Expect

Your B12 Visit, Step by Step

No special preparation is needed. Eat normally, stay hydrated and wear a top that gives easy access to your upper arm.

  1. Health Review

    We go over your medical history, medications, supplements, allergies and wellness goals, and answer your questions.

  2. Preparation

    The injection site on your upper arm is cleaned.

  3. Injection

    Your B12 is given with a small needle. The shot itself takes only moments.

  4. Back to Your Day

    Most people go straight back to their plans. The spot may feel a little sore or show a small bruise for a day or so. Tell us about any unusual reaction.

Dr. Natalie Mesnier, MD, founder of Ortho-Rejuv, in a black top and pearl necklace
Our Practice

Founded by Dr. Natalie Mesnier, MD

Founder · Medical Doctor

Dr. Mesnier founded our medical spa. Her certifications in advanced aesthetic procedures include PRP and neuromodulator applications.

B12 shots are given by our medical staff. Every shot begins with a conversation about your health, and our team helps you choose B12, IV therapy or a combination.

"Cassidy and Dr Mesnier were so knowledgeable about possible treatments that would work best for me."

Tonya Flaming, Google review
Combine It With

Pair B12 With Our Other Wellness Boosters

Add-On

B12 + IV Therapy

Add a B12 booster to an IV therapy appointment and take care of both in one visit.

IV Menu

IV Therapy

Fluids, vitamins, minerals and antioxidants delivered into the bloodstream, with blends for hydration, energy, immunity and skin health.

Quick Shot

MIC Shot

Another fast wellness booster on our menu. Ask our team whether it suits your goals alongside B12.

We are honest about what wellness shots can and cannot do. They support a healthy lifestyle, and they are not a substitute for medical care, sleep, nutrition and exercise.

Cost and Financing

B12 Shot Pricing and Membership

Choose a single visit or a booster add-on, and wellness program members receive member pricing. Current rates are on our medspa pricing page.

  • Single visit
  • Booster add-on to IV therapy
  • Wellness member pricing

We also offer financing through Cherry for wellness treatment plans.

FAQ

B12 Shot Questions

What Portland patients ask us most about B12 injections.

Is a B12 injection worth it?

It helps most for people who absorb B12 poorly or eat little animal food, because the shot does not rely on the gut. For others it is a convenient boost rather than a fix, and our team will tell you honestly which applies to you.

Can I get a B12 shot at a pharmacy instead?

Some pharmacies offer B12 injections, often depending on location and a prescription. With us, every shot starts with a review of your health history and goals, and B12 can be added to an IV therapy visit.

What is the best type of B12 injection?

No single form suits everyone. Our medical team selects the B12 that fits your health history after your review and explains why.

Do B12 shots help with weight loss?

B12 is not a weight-loss treatment on its own and does not replace nutrition, exercise or sleep. If weight management is a goal, ask our team about the MIC shot.

How often can I get a B12 shot in Portland, OR?

Our team recommends a schedule based on your health review, goals and response. Wellness program members receive member pricing on repeat visits.

How soon will I notice a difference?

Individual results vary. Some patients feel more energetic within days, while others notice little change, especially when their B12 levels were already normal.

Ready When You Are

Book Your B12 Shot in Portland

Come in for a stand-alone shot or add B12 to your next IV therapy visit. Consultations are free.

Visit Us

5050 NE Hoyt St #626
Portland, OR 97213

In the Providence Plaza building, across the street from Providence Hospital.

Hours

Mon to Thu 8am to 5pm
Fri 10am to 4pm
Sat 9am to 2pm
Sun closed

Venus Nova, Certified Advanced Esthetician at Ortho-Rejuv

Venus is a Certified Advanced Esthetician, Certified Phlebotomy Technician, and pre-nursing student with a passion for medical aesthetics and patient-centered care. She is dedicated to helping clients achieve healthy, radiant skin through result-driven, customized treatments tailored to their unique needs. As a patient advocate at heart, Venus loves working with all skin types and creating long-term skincare plans that focus on both visible results and overall skin health.

Her favorite treatments include Aerolase, NeoGen, and microneedling, innovative treatment options that deliver real, transformative outcomes. Outside of the treatment room, Venus enjoys creating social media content, exploring new food spots, and spending time with friends and family

Woman with long brown hair wearing black healthcare uniform against gray background

Certified Advanced Esthetician

Woman with long dark hair smiling at camera against white background
Katherine is a Certified Advanced Esthetician dedicated to helping every client feel confident and comfortable in their skin. She takes a personalized approach to skincare, creating customized treatment plans and at-home routines that work for you. Katherine is passionate about finding effective, thoughtful skincare solutions for all skin types and tones, with a special emphasis on acne-prone skin. She aims to provide a safe space in the treatment room to ensure every client feels welcomed and supported no matter where they are in their journey. She looks forward to meeting you soon!
Nancy, woman with long brown wavy hair wearing black top, smiling at camera
Dr. Nancy Yen Shipley experienced in the use of ultrasound and orthobiologics in the treatment of musculoskeletal conditions. And is additionally certified in Laser treatment of medical conditions, post-surgical and post-traumatic scars, PRP, injectable neuromodulators for medical and aesthetic applications.
Kyline, woman wearing white coat and gold chain necklace, smiling at camera
Ms. Kylie Farwell is a board-certified Physician Assistant and a native Idahoan. Trained in orthobiologics, PRP, ultrasound-guided interventions, laser therapy, and neuromodulators such as botox, and fillers, Kylie is passionate about helping patients overcome their post-surgical and post-traumatic scars, and present their best selves forward to the world.
Natalie, woman with shoulder-length dark hair wearing black top and pearl necklace

Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv Wellness and Aesthetics, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.