We treat volume loss, sun spots and crepey skin on the backs of the hands as three separate concerns, each with its own treatment, in one plan.
Upload a photo and preview how treatments at Ortho-Rejuv could look on you. Powered by Aesthetic Record’s Ageless AI.
See Your Potential
One patient, two hands. Only the hand on the right was treated, so the difference is easy to see: its skin looks smoother, with softer fine lines across the knuckles and the back of the hand.
The backs of the hands have thin skin and very little fat to begin with. They also get years of sun and rarely get sunscreen, so they can look older than the face.
A spot that grows, bleeds, itches or looks different from the others needs a medical check before any cosmetic treatment. We tell you if we see one.
Collagen and fat decrease with age, so veins and tendons become more visible and knuckles look bonier.
Years of sun exposure leave brown spots and uneven tone across the back of the hand.
Loss of elasticity leaves thin, finely wrinkled skin that creases when you make a fist.
Aging hands rarely show only one sign, so we treat by concern and combine what your hands need.
Visible veins and tendons, hollows between the bones.
Fillers and biostimulatorsSun spots, freckling and uneven pigment.
Aerolase laserThin, finely wrinkled skin that has lost its spring.
NeoGen plasma resurfacingMedical-grade chemical peels, SkinPen microneedling and Diamond Glow further improve tone and texture between or after your main treatments.

Dermal filler placed in the back of the hand adds a soft layer over veins and tendons, so they show less.
Collagen-stimulating biostimulators work differently: they prompt your own skin to rebuild support over the following weeks, for a gradual, longer-lasting result.
Two devices treat the surface of the skin, both run by our own team in Portland.
Targets sun spots and uneven pigment on the backs of the hands for a clearer, more even tone.
Uses nitrogen plasma energy to stimulate collagen and renew thin, crepey skin from beneath the surface. Results continue to develop over the following weeks.
"Recently I received a Neogen Plasma Resurfacing treatment at Ortho-Rejuv, and even though it's only my second week, I am really impressed with the results so far."
Robyn W., Google review
Most plans run over a few visits, in an order that lets each treatment build on the last.
We look at volume, pigment and texture on both hands and talk through your goals.
Free consultationWe recommend which treatments to combine, in what order, and quote the price.
Before any treatmentSessions take place in our Portland office. A microneedling session, for example, takes about 30 to 60 minutes.
Often a few visitsDaily sunscreen on your hands and occasional maintenance sessions keep the result.
OngoingHand rejuvenation is provided by our team of certified advanced estheticians and medical staff, who work with every skin type and tone.

Dr. Mesnier founded our medical spa and brings a background in aesthetic medicine, laser therapies, injectables and fillers.
The cost of hand rejuvenation depends on the treatments in your plan and how many sessions you need. We quote your price at the consultation, so you know it before you begin.
Many patients spread the cost of a treatment series with monthly payments through our financing partner, Cherry.
Prices for each treatment on our menu are listed on our medspa pricing page.
There is no single best treatment, because most aging hands show more than one sign. Fillers or biostimulators restore volume, the Aerolase laser targets sun spots, and NeoGen plasma, microneedling and peels improve crepey texture. We often combine them.
It depends on the treatments in your plan and the number of sessions. We quote your price at a free consultation, our current menu is on the medspa pricing page, and monthly payments are available through Cherry.
The backs of the hands have thin skin and little fat. As collagen and volume decrease with age, veins and tendons become easier to see. Filler in the back of the hand softens their look.
Yes. NeoGen plasma, SkinPen microneedling and medical-grade chemical peels all stimulate collagen, which helps thin, crepey skin look smoother over time.
It depends on how many signs you are treating and which treatments your plan uses. We map out the number and order of sessions at your consultation.
Wear sunscreen on the backs of your hands every day, since sun exposure causes new spots. Maintenance sessions help keep volume and texture where you want them.
Show us your hands, and leave with a plan for volume, spots and texture.
5050 NE Hoyt St #626, Portland, OR 97213 · Providence Plaza, across the street from Providence Hospital

Venus is a Certified Advanced Esthetician, Certified Phlebotomy Technician, and pre-nursing student with a passion for medical aesthetics and patient-centered care. She is dedicated to helping clients achieve healthy, radiant skin through result-driven, customized treatments tailored to their unique needs. As a patient advocate at heart, Venus loves working with all skin types and creating long-term skincare plans that focus on both visible results and overall skin health.
Her favorite treatments include Aerolase, NeoGen, and microneedling, innovative treatment options that deliver real, transformative outcomes. Outside of the treatment room, Venus enjoys creating social media content, exploring new food spots, and spending time with friends and family

Certified Advanced Esthetician




Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv Wellness and Aesthetics, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.