Collagen-stimulating injectables and PRF EZ-Gel made from your own plasma, planned around your face by our medical team so results build gradually and look like you.
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See Your PotentialHow It Works
Biostimulators are injectables that signal your skin to produce new collagen of its own. Rather than filling a line on the day, they rebuild the support underneath it.
Collagen production slows with age, and it shows as hollowing in the cheeks and temples, thinner skin and softer contours. A hyaluronic acid filler adds volume right away. A biostimulator works progressively, so firmness and support return over several weeks to months, and because the new collagen is yours, results can be long-lasting.
Collagen boosters can also be regenerative. Using a small sample of your own blood, we can concentrate platelets and growth factors or turn your plasma into a soft, natural filler.
Fine particles placed deep in the skin that your body gradually absorbs while it lays down new collagen around them. Usually planned as a short series for broader areas of volume loss.
A smooth gel carrying tiny mineral-based spheres. It gives structure where it is placed, then prompts collagen to form over the following months.
Boosters made from your own blood. PRF is rich in growth factors that support collagen and skin healing, and PRF EZ-Gel turns your plasma into a natural, gel-like filler.
Choosing Your Option
Many patients ask for filler when the real change is thinning skin, and others want a lift that only volume can give. This is how the three approaches differ, and why we often combine them.
| Biostimulator | Dermal Filler | PRF EZ-Gel | |
|---|---|---|---|
| Made From | PLLA or CaHA, materials the body gradually absorbs | Hyaluronic acid gel, including our RHA fillers | Your own blood plasma, processed into a gel |
| How It Works | Prompts your skin to build new collagen where it is placed | Adds volume and smooths lines where it is placed | Restores soft support with your own plasma and growth factors |
| When You See Change | Gradually, over weeks to months | Right after treatment | Soon after treatment, with a natural feel |
| Sessions | Often a series, spaced weeks apart | Often one visit, with touch-ups over time | Planned at your consultation |
| A Good Fit If | You want firmer skin and subtle, progressive change | You want visible volume or line correction now | You prefer to work with your own biology |
Candidates
Biostimulators and collagen boosters may suit adults in good health who want gradual, natural-looking improvement in volume and skin quality.
Want a visible change before a date on the calendar? A filler may suit you better, or a filler now with a biostimulator building support underneath. We also review your medical history and any contraindications first.
What to Expect
Collagen takes time to build, so the change is gradual by design. Here is how a typical plan unfolds.
Treatment Day
Product is placed in the planned areas. Some options give a little early fullness that settles in the first days.
First Few Days
Most patients are back to normal activities the same day. Mild redness, swelling or bruising usually fades within a few days.
Following Weeks
Your skin begins producing new collagen. If your plan is a series, the next session is scheduled in this window.
Several Months
Support, firmness and texture continue to improve for several months, for a refreshed look rather than a sudden one.
Our Practice
Dr. Mesnier founded our medical spa. Her background is in aesthetic medicine, with skill in anti-aging laser therapies, skin revitalization and the use of injectables and fillers, and she holds certifications in advanced aesthetic procedures, including PRP and neuromodulator applications.
Biostimulator and collagen booster treatments are provided by our medical staff and team of certified advanced estheticians. Rather than reaching for one product, our providers look at your skin structure as a whole and choose between PRF options, collagen-stimulating injectables and fillers based on what your face needs.
★★★★★
"Cassidy and Dr Mesnier were so knowledgeable about possible treatments that would work best for me."
Tonya Flaming, Google review
★★★★★
"Dr. Mesnier, Kylie, and Cassidy are so informative and Cassidy helped me through every step of my time."
Krystal Cook, Google review
The Process
Every plan begins with a consultation to understand your goals and see where volume and support have been lost. Your provider then recommends a biostimulator, a PRF-based treatment, a filler or a combination, and explains how many sessions may be needed.
We talk through your goals, assess your face and review your medical history, then map out the option and timeline that fit your anatomy.
The treatment area is cleansed and mapped, and comfort measures are applied as appropriate.
For PRF-based boosters, a small amount of blood is drawn and processed to concentrate platelets and growth factors. Our team includes a Certified Phlebotomy Technician.
Your provider places the product precisely in the planned areas to support collagen production and structure.
We review aftercare before you leave, which may include massage guidance for some products, and book any follow-up sessions in your series.
Most patients return to normal activities the same day. Mild redness, swelling, tenderness or bruising at the injection sites can occur and usually settles within a few days, while your results continue to develop for several months.
Combination Plans
Injectables rebuild support beneath the skin. Pairing them with treatments for the skin's surface gives a more complete result, and we plan the order and spacing for you.
Our dermal fillers, including RHA fillers, restore volume and smooth lines immediately while a biostimulator builds support underneath.
Growth factors from your own blood support collagen production and skin healing in the face.
Our FDA-approved SkinPen creates controlled micro-channels that prompt collagen, and can be paired with PRP for PRP Microneedling.
A plasma resurfacing treatment for texture and tone that pairs with injectables for more complete rejuvenation.
Investment
The cost of biostimulators and collagen boosters depends on the areas treated, the number of sessions in your plan and whether it is combined with other treatments. We give you an exact quote after your consultation, and current treatment and package pricing is listed on our medspa pricing page.
To make your plan easier to manage, we offer financing through Cherry, so you can spread the cost of your treatments over time.
FAQ
Still deciding between a biostimulator, a filler or PRF? Bring your questions to your consultation and we will walk through the options for your face.
Several do, in different ways. Biostimulator injectables such as poly-L-lactic acid and calcium hydroxylapatite prompt collagen where they are placed, while PRF uses growth factors from your own blood. Skin treatments we offer, including SkinPen microneedling and NeoGen Plasma Resurfacing, also work through your skin's collagen response, and we often pair them with injectables.
We plan with collagen-stimulating injectables in the PLLA and CaHA categories, PRF and PRF EZ-Gel made from your own blood, and dermal fillers including RHA fillers when you also want volume right away. Your provider recommends one option or a combination after looking at where support has been lost.
The cost depends on the areas treated, how many sessions your plan needs and whether it is combined with other treatments. We give you an exact quote after your consultation, and current treatment and package pricing is listed on our medspa pricing page. Financing through Cherry lets you spread the cost over time.
Results build gradually because your skin is producing new collagen. Most patients notice change over several weeks to months, and it may keep improving for several months after a session. Collagen-stimulating treatments are often planned as a series, so your full result arrives after the planned sessions.
Most patients return to normal activities the same day. Mild redness, swelling, tenderness or bruising at the injection sites can occur and usually settles within a few days. We go over aftercare before you leave, including massage guidance for some products.
PRF EZ-Gel is a regenerative option made from your own blood. A small sample is drawn and processed, and your plasma is turned into a natural, gel-like filler that is placed where support is needed. It suits patients who prefer to work with their own biology.
Yes, and many plans do. A filler restores volume right away, while a biostimulator builds support gradually underneath. Your provider decides the order and spacing so each treatment has room to do its part.
Start with a free consultation. We will look at where support has been lost and build a biostimulator, PRF or combination plan around your timeline.
5050 NE Hoyt St #626, Portland, OR 97213. We are in the Providence Plaza building, across the street from Providence Hospital.
Venus is a Certified Advanced Esthetician, Certified Phlebotomy Technician, and pre-nursing student with a passion for medical aesthetics and patient-centered care. She is dedicated to helping clients achieve healthy, radiant skin through result-driven, customized treatments tailored to their unique needs. As a patient advocate at heart, Venus loves working with all skin types and creating long-term skincare plans that focus on both visible results and overall skin health.
Her favorite treatments include Aerolase, NeoGen, and microneedling, innovative treatment options that deliver real, transformative outcomes. Outside of the treatment room, Venus enjoys creating social media content, exploring new food spots, and spending time with friends and family
Certified Advanced Esthetician
Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv Wellness and Aesthetics, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.
